KC244 - Bispecific Group Leader

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Posted: 16/01/2020 11:26
Start Date: Not Available
Salary: Competitive
Location: Babraham Research Campus, Cambridge, UK
Level: Scientific
Deadline: 27/03/2020 23:59
Hours: 35.00
Benefits: Excellent range of benefits
Job Type: Permanent

Kymab is a clinical-stage biopharmaceutical company developing a deep pipeline of novel antibody-based therapies in a broad range of indications. The Company generates its product candidates using its proprietary, integrated platforms collectively called IntelliSelect®. Kymab’s platforms have been designed to maximize the diversity of human antibodies produced in response to immunization with antigens. Selecting from a broad diversity of fully human antibodies allows for the identification of antibodies with optimal drug-like properties.

We are looking to recruit an outstanding laboratory-based group leader directly reporting to VP Technology & Bispecific Discovery group. You have an opportunity to lead a multidisciplinary team and leverage our IntelliSelect® Bispecifics technology to identify first-in-class bispecific antibodies for human disease treatment.

Key Responsibilities

  • Lead a multidisciplinary team to identify bispecific antibodies for drug discovery
  • Co-design a strategy with the supervisor for the bispecific antibody portfolio
  • Propose bispecific targets in the immuno-oncology and auto-immune areas
  • Propose the bispecific discovery research plans including MOA, target validation, functional screening and in vivo models to assess molecule efficacy
  • Lead bispecific discovery projects to Development Candidate stage
  • Co-develop the single cell sequence technology using microfluid to assess immune profiles with Antibody Discovery Group
  • Maintain accurate and up-to-date records of all proposals and experimentations

Job Requirements

Education & Experience

  • PhD, MD or MD/PhD equivalent degree in life science; more than 8 years of strong research background and experience in immunology, oncology or molecular biology
  • Strong track record and hands-on experience in immunology and single cell analysis is essential
  • Experience in protein expression from mammalian cell culture and assay development is an advantage
  • Line management experience is highly desirable
  • Knowledge and/or experience in bispecific antibody development would be highly desirable

Skills & Knowledge

  • Proven ability in immunology research areas
  • The ability to plan and execute to clear timelines
  • Proven understanding of intellectual property for new technologies
  • Strong organization skills with proven ability to analyze complicated data in a logical and understandable form
  • Leadership experience and ability to influence others

Competencies

  • Ability to multitask, work under pressure and prioritize work to meet deadlines
  • Excellent communication and presentation skills
  • Ability to motivate and influence others
  • A strong work ethic and enthusiasm to the assigned projects


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