KC209 - Senior Research Associate

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Posted: 02/05/2019 16:49
Start Date: Not Available
Salary: Competitive
Location: Babraham Research Campus, Cambridge, UK
Level: Scientific
Deadline: 02/09/2019 23:59
Hours: 35.00
Benefits: Excellent Range of Benefits
Job Type: Permanent

Kymab is a leading biopharmaceutical company focused on the discovery and development of fully human monoclonal antibody drugs using its proprietary IntelliSelect® antibody platform. Kymab was founded in 2010 and has since raised over US$220m of equity financing to advance several therapeutic antibody programmes in immune-oncology, auto-immunity, haematology and infectious disease. More information about Kymab can be found at www.kymab.com.

Reporting to the Antibody Discovery Group PCR Team lead, we are looking for a Senior Research Associate to form an integral part of Kymab’s core pipeline team, responsible for the high-throughput and improvement of the single cell sequencing workflows. You will be involved in projects from across the whole pipeline and key to driving forward the progression of projects towards the discovery of lead candidates to be selected for development.

KEY RESPONSIBILITIES:

•             Perform high-throughput single-cell PCR and NGS to recover B-cell repertoire

•             Drive improvement and validation of technology development projects

•             In-depth data analysis, visualisation and presentation of large data sets

•             Implement novel troubleshooting and QC procedures

•             Perform other methods related to the recovery of antibody DNA from cells

•             Effective organisation of daily tasks

•             Co-ordinate work with other members of the Antibody Discovery Group and other teams as required

•             Maintain accurate, high quality and up-to-date records of all experiments

•             Summarise and present results in internal meetings

•             Other duties as may be required

JOB REQUIREMENTS:

Education and Experience           

•             Educated to at least BSc or MSc (or equivalent industry experience) in a Biological science with relevant industry experience, or industrial placement year

•             Hands-on experience in a variety of molecular biology techniques (PCR, DNA cloning/sequencing, gel electrophoresis, etc.) is essential

•             Strong & demonstrable teamworking experience

•             Experience in NGS workflow & library preparation is desirable

•             Previous experience of working in automation is also desirable

Skills and Knowledge     

•             Working knowledge of a variety of core molecular biology techniques

•             Knowledge of high-throughput, single-cell PCR & NGS

•             Large data set analysis & analytical techniques

•             Knowledge or experience of R or Python scripting is highly desirable but not essential

•             High level of attention to detail

•             Ability to multi-task & prioritise workload across multiple projects

•             Excellent communication skills



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