KC209 - Senior Research Associate

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Posted: 02/05/2019 16:49
Start Date: Not Available
Salary: Competitive
Location: Babraham Research Campus, Cambridge, UK
Level: Scientific
Deadline: 02/09/2019 23:59
Hours: 35.00
Benefits: Excellent Range of Benefits
Job Type: Permanent

Kymab is a clinical-stage biopharmaceutical company developing a deep pipeline of novel antibody-based therapies in a broad range of indications. The Company generates its product candidates using its proprietary, integrated platforms collectively called IntelliSelect®. Kymab’s platforms have been designed to maximize the diversity of human antibodies produced in response to immunization with antigens. Selecting from a broad diversity of fully human antibodies allows for the identification of antibodies with optimal drug-like properties.

Reporting to the Antibody Discovery Group PCR Team lead, we are looking for a Senior Research Associate to form an integral part of Kymab’s core pipeline team, responsible for the high-throughput and improvement of the single cell sequencing workflows. You will be involved in projects from across the whole pipeline and key to driving forward the progression of projects towards the discovery of lead candidates to be selected for development.


•             Perform high-throughput single-cell PCR and NGS to recover B-cell repertoire

•             Drive improvement and validation of technology development projects

•             In-depth data analysis, visualisation and presentation of large data sets

•             Implement novel troubleshooting and QC procedures

•             Perform other methods related to the recovery of antibody DNA from cells

•             Effective organisation of daily tasks

•             Co-ordinate work with other members of the Antibody Discovery Group and other teams as required

•             Maintain accurate, high quality and up-to-date records of all experiments

•             Summarise and present results in internal meetings

•             Other duties as may be required


Education and Experience           

•             Educated to at least BSc or MSc (or equivalent industry experience) in a Biological science with relevant industry experience, or industrial placement year

•             Hands-on experience in a variety of molecular biology techniques (PCR, DNA cloning/sequencing, gel electrophoresis, etc.) is essential

•             Strong & demonstrable teamworking experience

•             Experience in NGS workflow & library preparation is desirable

•             Previous experience of working in automation is also desirable

Skills and Knowledge     

•             Working knowledge of a variety of core molecular biology techniques

•             Knowledge of high-throughput, single-cell PCR & NGS

•             Large data set analysis & analytical techniques

•             Knowledge or experience of R or Python scripting is highly desirable but not essential

•             High level of attention to detail

•             Ability to multi-task & prioritise workload across multiple projects

•             Excellent communication skills

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